Endocrine Abstracts

Type 2 diabetes mellitus (DM2) is often associated with obstructive sleep apnea (OSA), according to the literature. Current approach in choosing the hypoglycemic therapy is based on individualization, but do not take into account the effect on OSA. The research purpose: to evaluate the effect of various hypoglycemic agents on the characteristics of OSA in patients with type 2 diabetes.Materials and methods: The study included patients with OSA and DM2, t...

Patients with type 2 diabetes mellitus (DM) are one of the most vulnerable categories of patients in terms of adverse outcomes of COVID-19 infection.Aim: To assess the features of laboratory and instrumental data in patients with COVID-19 and type 2 DM (unvaccinated) depending on the value of glycated hemoglobin (HbA1c) at the time of the onset of oxygen deficiency.Materials and methods: The study involved 78 patients with type 2 D...

Recent evidence points to a relationship between the severity of Covid-19 infection and iron metabolism. In patients with type 2 diabetes mellitus (DM 2), the prevalence of anemia of chronic diseases exceeds the general population indicators, which may be one of the factors determining the increase in mortality in this category of patients with Covid-19.Aim: To determine the differences between markers of ferrostatus indicators in patients with DM 2 and ...

Objective: To determine the effects of hypoglycemia while sleeping on somnological parameters for patients with type 1 DM.Materials and methods: The study included 57 person with type 1 DM (Group 1 – patients with blood glucose levels (BGL) during sleep <3.9 mmol/l; Group 2 – Patients with BGL – from 3.9 to 10.0 mmol/l. The examination included: daily monitoring of blood glucose by ‘CGMSGold’ (‘MedtronikMINIMED’ (US...

Objective: To establish the differences in terms of sleep for patients with type 1 diabetes, depending on the level of blood glucose levels (BGL) during the night.Materials and methods: The study included 43 participants with type 1 diabetes (Group A – patients with BGL during sleep from 3.9 to 7.4 mmol/l, Group B – 7.5–10.0 mmol/l. Patients had daily monitoring of BGL ‘CGMSGold’ by ‘MedtronikMINIMED’ (USA), polysomnogr...

It is determined that sleep apnea itself can affect the level of HbA1c, thereby affecting the compensation of carbohydrate metabolism in type 2 diabetes.Objective: To determine the quantity and type of sleep apnea in diabetes type 1, depending on the level of HbA1c.Materials and methods: The study involved 50 people with type 1 diabetes without the presence of diabetic autonomic neuropathy or diseases of the pulmonary system and EN...

Objective: Assessing the impact of glycaemic control on indicators of breathing during night sleep in type 1 diabetes patients.Methods: Continuous blood glucose monitoring by ‘SGMSGold’ (Medtronik MINIMED) with estimation of average glycaemic value (AG) and other parameters; polysomnographic monitoring by ‘SOMNOlab 2 (PSG) Polysomnography (R&K)’. Group 1 included patients with AG levels <8.0. Group 2: AG >8.0 mmol/l regard...

Study evaluates the impact of glycemia on the parameters of night’s sleep for patients with decompensated type 1 diabetes mellitus (T1DM).Materials and methods: A total of 21 cases with T1DM (HBA1C 8.5%). The monitoring of the average daily glycemia was performed through ‘SGMSGold Medtronik’ (USA) with estimation of average level of glucose (ALG). Patients divided into groups: group A – 10 patients with A...

Fluctuations of glycemia, the rate of glycemia decreasing, the chronic decompensation type 1 diabetes adversely influenceon diabetic complications development. Increased glycemia during sleep leads to a change in the structure of sleep and a decrease in its functions.The aim of the study was to assess the effect of glycemic values and it’s correction during sleep on somnological indicators.Materials and methods: The study incl...

The Sars-COV-2 virus is a recognized endocrine disruptor, which determines the possibility of endocrine dysfunctions associated with COVID 19. One of the endocrine diseases associated with COVID 19 is subacute thyroiditis (STh), which develops regardless of the severity of manifestations of the underlying disease. The aim of the study: to evaluate the clinical manifestations, therapy, and outcomes of STh in unvaccinated COVID 19 patients.Materials and me...